Recombinant Mouse Abhd11 Protein, Myc/DDK-tagged
Cat.No. : | Abhd11-1466M |
Product Overview : | Purified recombinant protein of mouse full-length abhydrolase domain containing 11 (Abhd11), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | Ubiquitous expression in large intestine adult (RPKM 44.7), colon adult (RPKM 41.1) and 28 other tissues. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 33.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Abhd11 abhydrolase domain containing 11 [ Mus musculus (house mouse) ] |
Official Symbol : | Abhd11 |
Synonyms : | ABHD11; abhydrolase domain containing 11; abhydrolase domain-containing protein 11; Williams-Beuren syndrome critical region 21; Williams Beuren syndrome chromosome region 21; Williams-Beuren syndrome chromosomal region 21 protein homolog; Wbscr21; 1110054D16Rik; A630008N09Rik |
Gene ID : | 68758 |
mRNA Refseq : | NM_001190437 |
Protein Refseq : | NP_001177366 |
UniProt ID : | D3YYK0 |
Products Types
◆ Recombinant Protein | ||
ABHD11-1747M | Recombinant Mouse ABHD11 Protein (1-307 aa), His-tagged | +Inquiry |
ABHD11-1062M | Recombinant Mouse ABHD11 Protein (1-307 aa), His-SUMO-tagged | +Inquiry |
ABHD11-1236Z | Recombinant Zebrafish ABHD11 | +Inquiry |
ABHD11-072H | Recombinant Human ABHD11 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
ABHD11-9140HCL | Recombinant Human ABHD11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionABHD11 is a potential biomarker of lung adenocarcinoma, and is linked to breast cancer malignancy.
ABHD11 loss or inhibition drives a rapid increase in 2-OG levels by impairing lipoylation of the 2-OG dehydrogenase complex (OGDHc)—the rate limiting step for mitochondrial 2-OG metabolism.
ABHD11 is one of several genes deleted in Williams–Beuren syndrome, a developmental disorder associated with haploinsufficiency of multiple genes.
The results of bioinformatic analysis demonstrated that ABHD11 and ABHD10 were downregulated, while most other ABHD family genes, such as Abhd 1, 3, 5, 6, and 7 were upregulated in OCT4-negative cells.
ABHD11 knockout disturbed GSK3β/β-Catenin and ERK signaling transduction; ABHD11 knockout led to the misexpression of key metabolic enzymes related to lipid synthesis, glycolysis, and amino acid metabolism.
The ABHD11 often as a prognostic marker of renal cancer.
Kidney - Transmembrane transport (mainly)
In yeast, the overexpression of ABHD11 or its yeast homolog causes a reduction in the levels of non-polar lipids.
1. plasma membrane, 2. endosome, 3. mitochondrion
This results suggested that the ABHD11 gene promote cancer cell proliferation, metastasis, and invasion, and inhibit cancer cell apoptosis.
Customer Reviews (4)
Write a reviewGreat work on ELISA with recommended dilution !
Excellent quality products!
We are satisfied with the WB results of ABHD11 product.
After-sales questions were answered in a timely manner. Good!
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