Recombinant Zebrafish ABHD11
Cat.No. : | ABHD11-1236Z |
Product Overview : | Recombinant Zebrafish ABHD11 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | abhd11 abhydrolase domain containing 11 [ Danio rerio (zebrafish) ] |
Official Symbol : | ABHD11 |
Gene ID : | 446169 |
mRNA Refseq : | NM_001004290 |
Protein Refseq : | NP_001004290 |
UniProt ID : | Q6DRD9 |
Products Types
◆ Recombinant Protein | ||
ABHD11-1747M | Recombinant Mouse ABHD11 Protein (1-307 aa), His-tagged | +Inquiry |
Abhd11-1466M | Recombinant Mouse Abhd11 Protein, Myc/DDK-tagged | +Inquiry |
ABHD11-1062M | Recombinant Mouse ABHD11 Protein (1-307 aa), His-SUMO-tagged | +Inquiry |
ABHD11-072H | Recombinant Human ABHD11 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
ABHD11-9140HCL | Recombinant Human ABHD11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionABHD11 is a potential biomarker of lung adenocarcinoma, and is linked to breast cancer malignancy.
ABHD11 loss or inhibition drives a rapid increase in 2-OG levels by impairing lipoylation of the 2-OG dehydrogenase complex (OGDHc)—the rate limiting step for mitochondrial 2-OG metabolism.
ABHD11 is one of several genes deleted in Williams–Beuren syndrome, a developmental disorder associated with haploinsufficiency of multiple genes.
The results of bioinformatic analysis demonstrated that ABHD11 and ABHD10 were downregulated, while most other ABHD family genes, such as Abhd 1, 3, 5, 6, and 7 were upregulated in OCT4-negative cells.
ABHD11 knockout disturbed GSK3β/β-Catenin and ERK signaling transduction; ABHD11 knockout led to the misexpression of key metabolic enzymes related to lipid synthesis, glycolysis, and amino acid metabolism.
The ABHD11 often as a prognostic marker of renal cancer.
Kidney - Transmembrane transport (mainly)
In yeast, the overexpression of ABHD11 or its yeast homolog causes a reduction in the levels of non-polar lipids.
1. plasma membrane, 2. endosome, 3. mitochondrion
This results suggested that the ABHD11 gene promote cancer cell proliferation, metastasis, and invasion, and inhibit cancer cell apoptosis.
Customer Reviews (4)
Write a reviewGreat work on ELISA with recommended dilution !
Excellent quality products!
We are satisfied with the WB results of ABHD11 product.
After-sales questions were answered in a timely manner. Good!
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