Recombinant Mouse ACOT1 Protein

• Cat.No.: ACOT1-1195M
• Product Overview: Recombinant Mouse ACOT1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Acot1 acyl-CoA thioesterase 1 [ Mus musculus ]
• Official Symbol: ACOT1
• Gene ID: 26897
• mRNA Refseq: NM_012006.2
• Protein Refseq: NP_036136.1
• UniProt ID: O55137

Q&As

Are there any mutations in the ACOT1 gene associated with disease?

Several genetic mutations in the ACOT1 gene have been associated with metabolic disorders, including obesity and insulin resistance.

What is the subcellular localization of ACOT1 protein?

ACOT1 protein is localized in the cytoplasm of cells.

What is the role of ACOT1 in lipid metabolism?

ACOT1 plays a crucial role in lipid metabolism by hydrolyzing long-chain acyl-CoA thioesters, which are intermediates in the beta-oxidation of fatty acids, and releasing free fatty acids that can be utilized for energy production or other metabolic processes.

Is ACOT1 expressed in all tissues?

ACOT1 is expressed in a variety of tissues, including the liver, heart, skeletal muscle, and brain.

What is the physiological significance of ACOT1?

ACOT1 is important for energy metabolism and is involved in regulating lipid storage and utilization. It has also been implicated in the development of obesity, metabolic disorders and cancer.

Is ACOT1 a membrane-bound protein?

ACOT1 is a soluble protein that is not membrane-bound.