Recombinant Rat ASAP1 Protein, His (Fc)-Avi-tagged

• Cat.No.: ASAP1-472R
• Product Overview: Recombinant Rat ASAP1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rat
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [ Rattus norvegicus ]
• Official Symbol: ASAP1
• Gene ID: 314961
• mRNA Refseq: NM_001044245.1
• Protein Refseq: NP_001037710.1
• UniProt ID: Q1AAU6

Reviews

12/25/2020

I have found the ASAP1 Protein to be highly stable, enabling long-term experiments without compromising its performance.

05/08/2019

One aspect that sets the ASAP1 Protein apart is the excellent technical support provided by the manufacturer.

01/09/2016

The ASAP1 Protein is an exceptional product that fully meets my experimental needs.

Q&As

How does ASAP1 participate in actin cytoskeleton remodeling?

ASAP1 binds to actin-binding proteins and actin regulatory proteins, enabling it to regulate actin dynamics and cytoskeleton rearrangements in response to cellular signaling.

What cellular processes are regulated by ASAP1's Arf-GAP activity?

ASAP1's Arf-GAP activity influences processes such as endocytosis, exocytosis, membrane recycling, and protein trafficking.

Is ASAP1 expression altered in cancer?

Yes, ASAP1 expression levels can be dysregulated in certain cancer types, leading to increased invasiveness and poor prognosis.

Does ASAP1 play a role in cancer development or progression?

Yes, ASAP1 has been implicated in cancer progression, promoting cell migration, invasion, and metastasis.

Where is ASAP1 primarily localized within cells?

ASAP1 is found predominantly at the plasma membrane, where it participates in various cellular activities.

What other proteins interact with ASAP1?

ASAP1 interacts with various proteins, including members of the Arf family, components of the endocytic machinery, regulators of actin dynamics, and other signal transduction molecules.

Are there any mutations or genetic variations associated with ASAP1?

Mutations or genetic variations in ASAP1 have not been extensively reported, but further research is required to explore their potential associations.