Recombinant Zebrafish ALG14
Cat.No. : | ALG14-1598Z |
Product Overview : | Recombinant Zebrafish ALG14 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit [ Danio rerio (zebrafish) ] |
Official Symbol : | ALG14 |
Gene ID : | 450072 |
mRNA Refseq : | NM_001006092 |
Protein Refseq : | NP_001006092 |
UniProt ID : | Q5XJS2 |
Products Types
◆ Recombinant Protein | ||
ALG14-285R | Recombinant Rat ALG14 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALG14-465M | Recombinant Mouse ALG14 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALG14-9574H | Recombinant Human ALG14, His-tagged | +Inquiry |
ALG14-1545M | Recombinant Mouse ALG14 Protein | +Inquiry |
ALG14-629R | Recombinant Rat ALG14 Protein | +Inquiry |
◆ Lysates | ||
ALG14-8907HCL | Recombinant Human ALG14 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (18)
Ask a questionOverexpression or knockout of ALG14 may negatively affect cellular glycosylation and the stability of ER and Golgi bodies, but the specific effects need to be further explored.
The relationship between ALG14 and neurological diseases needs further study, but it is known to be associated with diseases such as intellectual deficiency and idiopathic epilepsy.
ALG14 mutations have been shown to be associated with a variety of neurological disorders such as intellectual impairment and idiopathic epilepsy.
ALG14 is involved in metabolic pathways such as glycosylation and glucose metabolism, and has important biological functions.
ALG14 is mainly distributed in the endoplasmic reticulum (ER) and the Golgi apparatus.
ALG14 is involved in several biological processes including protein glycosylation, ER and Golgi body sugar metabolism.
ALG14, as a member of UDP-glucose-glycosyltransferase, is involved in the synthesis and modification of sugar chains during glycosylation, and plays an important role in the glycosylation and modification of post-translational mitochondrial proteins and plasma membrane proteins.
This protein can selectively catalyze the specific chemical structure of sugar chains, thereby affecting the biological properties and function of proteins.
This is an important UDP-glucose-glycosyltransferase. It plays a very important role in protein glycosylation and cell growth.
As a member of the UDP-glucose-glycosyltransferase family, ALG14 is functionally similar to ALG13, ALG1 and other family members.
Although the function of ALG14 in the non-cellular autophagy pathway has not been clearly studied, there are indications that it may be involved in the TCA cycle and gluconeogenic pathway.
This protein can influence the specific structure, length and branching of sugar chains through selective glycosylation reactions.
ALG14 interacts with glycosylation enzymes such as ALG13, ALG1 and mannosyltransferase to jointly regulate the glycosylation process of proteins.
ALG14 may be involved in mitochondrial glucose metabolism, although more research is needed to investigate the specific mechanism.
There is currently no direct evidence that ALG14 is associated with the onset and development of diabetes, but glycosylation plays a key role in metabolism and disease development, so it may be involved in diabetes.
No studies have shown that ALG14 is directly related to the occurrence of neurodegenerative diseases, but glycosylation plays a crucial role in the development and function of the nervous system, so it may be related to neurodegenerative diseases.
The regulates the expression of glycosylase and the balance of glycosylation reaction by interacting with other glycosylated enzymes such as ALG13 and ALG1.
Several inhibitors have been developed to target ALG14, including inhibiting its glycosylation activity and regulating its interactions with other glycosylated enzymes.
Customer Reviews (3)
Write a reviewCatalyze the hydrolysis of clindamycin phosphate to clindamycin, and make it play an antibiotic role.
ALG14 had high purity and no obvious impurities.
Can be detected by AGAR electrophoresis method, it is convenient.
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