Recombinant Human ADAMTS5 Protein, His (Fc)-Avi-tagged

• Cat.No.: ADAMTS5-2425H
• Product Overview: Recombinant Human ADAMTS5 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 [ Homo sapiens ]
• Official Symbol: ADAMTS5
• Synonyms: ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADMP-2; ADAMTS11; FLJ36738; ADAMTS5; a disintegrin and metalloproteinase with thrombospondin motifs 5; ADAM-TS5; ADAM-TS 5; ADAMTS-11; ADAM-TS 11; aggrecanase-2; a disintegrin and metalloproteinase with thrombospondin motifs 11; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); EC 3.4.24.
• Gene ID: 11096
• mRNA Refseq: NM_007038
• Protein Refseq: NP_008969
• MIM: 605007
• UniProt ID: Q9UNA0

Reviews

06/24/2020

The staff was very nice, communicated with me positively and solved a lot of technical problems.

06/19/2020

The ADAMTS5 proteins purchased from your company is suitable for ELISA.

06/17/2020

Fast and timely shipment helped me to get satisfactory experimental results in short time.

Q&As

Do you offer ADAMTS5 fused with other tags?

We can provide you with the most suitable labels according to your experimental needs.

ADAMTS5 is used in studies of which diseases?

ADAMTS5 is used in the study of oral squamous cell carcinoma, gastric cancer, and many other cancers.

How does ADAMTS5 relate to Aggrecan?

ADAMTS5 can cut Aggrecan.

What is the structure domain of ADAMTS5?

DAMTS5 is composed of a signal peptide, a pro-domain, a catalytic metalloproteinase domain, a disintegrin-like domain, and other C-terminal ancillary domains (a central thrombospondin type 1 sequence repeat (central TSR) motif, a cysteine-rich domain, a spacer region, and an additional TSR motif).

What biological processes is ADAMTS5 involved in?

ADAMTS5 is involved in the degradation of polyproteoglycans.