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DEFB103A

  • Official Full Name

    defensin, beta 103A

  • Overview

    Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.
  • Synonyms

    DEFB103A; defensin, beta 103A; DEFB3, DEFB103, defensin, beta 3; beta-defensin 103; DEFB 3; HBD 3; HBD3; HBP 3; HBP3; beta-defensin 3; defensin, beta 3; defensin, beta 103; defensin-like protein; BD-3; DEFB3; HBP-3; hBD-3; DEFB-3; DEFB103;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • E.coli
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His
  • N/A
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DEFB103A-84H Recombinant Human DEFB103A protein E.coli N/A 45
Human DEFB103A-2522H Recombinant Human DEFB103A Protein, GST-tagged Wheat Germ GST
Human DEFB103A-85H Recombinant Human DEFB103A protein, His-tagged E.coli His Gly 23-Lys 67
Human DEFB103A-7304H Recombinant Human DEFB103A protein, His-tagged E.coli His Gly23-Lys67
Human DEFB103A-464HCL Recombinant Human DEFB103A cell lysate N/A
Human DEFB103A-541H Active Recombinant Human DEFB103A Protein E.coli Tag Free
Human DEFB103A-2431HF Recombinant Full Length Human DEFB103A Protein, GST-tagged In Vitro Cell Free System GST 67 amino acids
Human DEFB103A-301628H Recombinant Human DEFB103A protein, GST-tagged E.coli GST Met23-Lys67
Human DEFB103A-69H Active Recombinant Human DEFB103A Protein E.coli
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DEFB103A Related Articles
  • DEFB103A Related Research Area

DEFB103A involved in several pathways and played different roles in them. We selected most pathways DEFB103A participated on our site, such as Beta defensins, Defensins, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with DEFB103A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Beta defensinsDEFB125;DEFB104A;CCR6;DEFB4B;DEFB103A;DEFB106A;DEFB129;DEFB4A;DEFB116
DefensinsDEFA3;CCR6;ART1;DEFB104A;DEFB4B;DEFB116;DEFB125;DEFB129;DEFB4A
Immune SystemSIGLEC15;GAN;KLC3;CD300C;BLMH;OSCAR;MGC174152;PLD4;BTR06
Innate Immune SystemSIRPB1;CASP4;RNF216;CRP;FCN2;TNRC5;ABI1;BTR02;HERC5

DEFB103A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DEFB103A itself. We selected most functions DEFB103A had, and list some proteins which have the same functions with DEFB103A. You can find most of the proteins on our site.

Function Related Protein

DEFB103A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEFB103A here. Most of them are supplied by our site. Hope this information will be useful for your research of DEFB103A.

Nuding, S; Gersemann, M; et al. Gastric Antimicrobial Peptides Fail to Eradicate Helicobacter pylori Infection Due to Selective Induction and Resistance. PLOS ONE 8:-(2013).
Mehlotra, RK; Zimmerman, PA; et al. Variation in human -defensin genes: new insights from a multi-population study. INTERNATIONAL JOURNAL OF IMMUNOGENETICS 40:261-269(2013).
  • Q&As
  • Reviews

Q&As (5)

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What specific clinical conditions are associated with DEFB103A deficiency? 02/14/2023

DEFB103A deficiency has been linked to an increased susceptibility to various infections, particularly those affecting the skin and mucosal surfaces.

Are there any side effects or concerns associated with the therapeutic use of DEFB103A? 11/22/2021

While research is ongoing, potential side effects and concerns related to the therapeutic use of DEFB103A or its analogs need to be thoroughly investigated, including any possible immunogenicity.

How does DEFB103A interact with the human microbiome? 02/13/2019

DEFB103A plays a role in maintaining a balanced microbiome by exerting selective antimicrobial activity. Understanding this interaction is crucial for potential applications in microbiome-related disorders.

In what ways does DEFB103A play a role in inflammatory diseases? 07/05/2017

DEFB103A is implicated in modulating inflammation. It can influence the immune response and may have a role in inflammatory conditions such as psoriasis and inflammatory bowel disease.

How does DEFB103A contribute to the immune system? 02/27/2017

DEFB103A plays a crucial role in the innate immune system by acting as an antimicrobial peptide. It helps defend the body against a wide range of pathogens, including bacteria, viruses, and fungi.

Customer Reviews (3)

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Reviews
10/11/2022

    This unique capability to selectively bind to exposed PS simplifies the identification and quantification of different cellular populations, reducing experimental errors and enhancing accuracy.

    06/23/2018

      They can provide technical assistance, ensuring optimal utilization of the product.

      10/28/2017

        This may include providing detailed protocols, troubleshooting guidance, and access to knowledgeable experts who can answer any inquiries or concerns.

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