Recombinant Human ADAMTS5 protein, His & T7-tagged
Cat.No. : | ADAMTS5-1755H |
Product Overview : | Recombinant Human ADAMTS5 aa. (Glu485~Pro622 (Accession # Q9UNA0)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 19.0kDa |
Protein length : | Glu485~Pro622 (Accession # Q9UNA0) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 9.3 |
Gene Name : | ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 [ Homo sapiens (human) ] |
Official Symbol : | ADAMTS5 |
Synonyms : | ADAMTS5; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; a disintegrin and metalloproteinase with thrombospondin motifs 11; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); aggrecanase-2 |
Gene ID : | 11096 |
mRNA Refseq : | NM_007038.4 |
Protein Refseq : | NP_008969.2 |
UniProt ID : | Q9UNA0 |
Products Types
◆ Recombinant Protein | ||
ADAMTS5-2037M | Recombinant Mouse ADAMTS5 Protein (262-930 aa), His-tagged | +Inquiry |
ADAMTS5-144H | Active Recombinant Human ADAMTS5 Protein, His-tagged | +Inquiry |
ADAMTS5-2425H | Recombinant Human ADAMTS5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Adamts5-1756R | Recombinant Rat Adamts5 protein, His & T7-tagged | +Inquiry |
ADAMTS5-534H | Active Recombinant Human ADAMTS5, His-tagged | +Inquiry |
◆ Lysates | ||
ADAMTS5-9028HCL | Recombinant Human ADAMTS5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionWe can provide you with the most suitable labels according to your experimental needs.
ADAMTS5 is used in the study of oral squamous cell carcinoma, gastric cancer, and many other cancers.
ADAMTS5 can cut Aggrecan.
DAMTS5 is composed of a signal peptide, a pro-domain, a catalytic metalloproteinase domain, a disintegrin-like domain, and other C-terminal ancillary domains (a central thrombospondin type 1 sequence repeat (central TSR) motif, a cysteine-rich domain, a spacer region, and an additional TSR motif).
ADAMTS5 is involved in the degradation of polyproteoglycans.
Customer Reviews (3)
Write a reviewThe staff was very nice, communicated with me positively and solved a lot of technical problems.
The ADAMTS5 proteins purchased from your company is suitable for ELISA.
Fast and timely shipment helped me to get satisfactory experimental results in short time.
Ask a Question for All ADAMTS5 Products
Required fields are marked with *
My Review for All ADAMTS5 Products
Required fields are marked with *
Inquiry Basket