Recombinant Human ALDH1A3 Protein, GST-tagged
Cat.No. : | ALDH1A3-440H |
Product Overview : | Human ALDH1A3 full-length ORF (BAG35229.1, 1 a.a. - 512 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 82.72 kDa |
AA Sequence : | MATANGAVENGQPDRKPPALPRPIR NLEVKFTKIFINNEWHESKSGKKFA TCNPSTREQICEVEEGDKPDVDKAV EAAQVAFQRGSPWRRLDALSRGRLL HQLADLVERDRATLAALETMDTGKP FLHAFFIDLEGCIRTLRYFAGWADK IQGKTIPTDDNVVCFTRHEPIGVCG AITPWNFPLLMLVWKLAPALCCGNT MVLKPAEQTPLTALYLGSLIKEAGF PPGVVNIVPGFGPTVGAAISSHPQI NKIAFTGSTEVGKLVKEAASRSNLK RVTLELGGKNPCIVCADADLDLAVE CAHQGVFFNQGQCCTAASRVFVEEQ VYSEFVRRSVEYAKKRPVGDPFDVK TEQGPQIDQKQFDKILELIESGKKE GAKLECGGPAMEDKGLFIKPTVFSE VTDNMRIAKEEIFGPVQPILKFKSI EEVIKRANSTDYGLTAAVFTKNLDK ALKLASALESGTVWINCYNALYAQA PFGGFKMSGNGRELGEYALAEYTEV KTVTIKLGDKNP |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ALDH1A3 aldehyde dehydrogenase 1 family, member A3 [ Homo sapiens ] |
Official Symbol : | ALDH1A3 |
Synonyms : | ALDH1A3; aldehyde dehydrogenase 1 family, member A3; ALDH6; aldehyde dehydrogenase family 1 member A3; RALDH3; retinaldehyde dehydrogenase 3; RALDH-3; aldehyde dehydrogenase 6; acetaldehyde dehydrogenase 6; ALDH1A6; |
Gene ID : | 220 |
mRNA Refseq : | NM_000693 |
Protein Refseq : | NP_000684 |
MIM : | 600463 |
UniProt ID : | P47895 |
Products Types
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◆ Lysates | ||
ALDH1A3-8919HCL | Recombinant Human ALDH1A3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionALDH1A3 has been implicated in cancer stem cell maintenance and differentiation, making it a potential target for cancer therapy.
ALDH1A3 has implications beyond cancer, and its role in retinoic acid metabolism suggests potential therapeutic applications in developmental disorders and other diseases.
ALDH1A3 is involved in the EMT process, a crucial step in cancer metastasis, highlighting its significance in tumor invasion and spread.
ALDH1A3 overexpression has been observed in various cancers, including breast, lung, ovarian, and pancreatic cancers.
Clinical trials are exploring the therapeutic potential of targeting ALDH1A3, evaluating the safety and efficacy of novel drugs in cancer patients.
Customer Reviews (3)
Write a reviewThe combination of high-quality ALDH1A3 protein and excellent technical support provided by the manufacturer makes them the ideal choice for my research.
The manufacturer's extensive experience and expertise in the field of ALDH1A3 protein research make them a trusted partner.
The manufacturer's commitment to providing excellent technical support is highly valuable.
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