Recombinant Human ALDH1A3 protein, His-tagged

• Cat.No.: ALDH1A3-1158H
• Product Overview: Recombinant Human ALDH1A3 protein(NP_000684.2)(Ala2-Pro512), fused with His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied as sterile PBS 7.4 10% glycerol 0.2% TWEEN20Please contact us for any concerns or special requirements.Please refer to the specific buffer information in the hard copy of CoA.
• Molecular Mass: The recombinant human ALDH1A3 consisting of 518 amino acids and migrates as an approximately 57 kDa band in SDS-PAGE under reducing conditions as predicted.
• Protein Length: Ala2-Pro512
• Purity: > 96 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: ALDH1A3 aldehyde dehydrogenase 1 family, member A3 [ Homo sapiens ]
• Official Symbol: ALDH1A3
• Synonyms: ALDH1A3; aldehyde dehydrogenase 1 family, member A3; ALDH6; aldehyde dehydrogenase family 1 member A3; RALDH3; retinaldehyde dehydrogenase 3; RALDH-3; aldehyde dehydrogenase 6; acetaldehyde dehydrogenase 6; ALDH1A6
• Gene ID: 220
• mRNA Refseq: NM_000693
• Protein Refseq: NP_000684
• MIM: 600463
• UniProt ID: P47895

Reviews

04/27/2022

The combination of high-quality ALDH1A3 protein and excellent technical support provided by the manufacturer makes them the ideal choice for my research.

11/05/2020

The manufacturer's extensive experience and expertise in the field of ALDH1A3 protein research make them a trusted partner.

10/14/2016

The manufacturer's commitment to providing excellent technical support is highly valuable.

Q&As

How is ALDH1A3 protein clinically relevant?

ALDH1A3 has been implicated in cancer stem cell maintenance and differentiation, making it a potential target for cancer therapy.

Can ALDH1A3 be a potential therapeutic target beyond cancer?

ALDH1A3 has implications beyond cancer, and its role in retinoic acid metabolism suggests potential therapeutic applications in developmental disorders and other diseases.

How does ALDH1A3 contribute to the epithelial-mesenchymal transition (EMT) process?

ALDH1A3 is involved in the EMT process, a crucial step in cancer metastasis, highlighting its significance in tumor invasion and spread.

In which cancers is ALDH1A3 protein overexpressed?

ALDH1A3 overexpression has been observed in various cancers, including breast, lung, ovarian, and pancreatic cancers.

Are there any ongoing clinical trials targeting ALDH1A3?

Clinical trials are exploring the therapeutic potential of targeting ALDH1A3, evaluating the safety and efficacy of novel drugs in cancer patients.