Recombinant Human SLC5A2 Protein (1-102 aa), His-Myc-tagged
Cat.No. : | SLC5A2-2210H |
Product Overview : | Recombinant Human SLC5A2 Protein (1-102 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Signal Transduction. Protein Description: Partial. |
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Description : | Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules. |
Source : | E. coli |
Species : | Human |
Tag : | His-Myc |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 15.5 kDa |
Protein length : | 1-102 aa |
AA Sequence : | MEEHTEAGSAPEMGAQKALIDNPAD ILVIAAYFLLVIGVGLWSMCRTNRG TVGGYFLAGRSMVWWPVGASLFASN IGSGHFVGLAGTGAASGLAVAGFEW NA |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 [ Homo sapiens ] |
Official Symbol : | SLC5A2 |
Synonyms : | SLC5A2; SGLT2; sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; |
Gene ID : | 6524 |
mRNA Refseq : | NM_003041 |
Protein Refseq : | NP_003032 |
MIM : | 182381 |
UniProt ID : | P31639 |
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◆ Lysates | ||
SLC5A2-1709HCL | Recombinant Human SLC5A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSLC5A2 inhibitors may have implications beyond diabetes, including potential cardiovascular and renal protective effects.
The SLC5A2 protein plays a crucial role in maintaining normal blood glucose levels by reabsorbing filtered glucose from the urine back into the bloodstream.
Genetic testing for SLC5A2 mutations can help identify individuals with renal glycosuria or other related conditions.
Pharmaceutical companies are developing SGLT2 inhibitors, which can selectively block the activity of the SLC5A2 protein to reduce glucose reabsorption in the kidneys.
In individuals with SLC5A2 mutations, the increased excretion of glucose in the urine may predispose them to urinary tract infections and dehydration.
Customer Reviews (3)
Write a reviewIts stability and compatibility make it an excellent tool for visualizing and characterizing protein structures at high resolution.
The SLC5A2 protein stands out for its exceptional quality, making it an excellent choice to meet my experimental requirements.
the SLC5A2 protein's compatibility with various experimental techniques adds to its versatility.
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