Brief Introduction

Creative BioMart provides you with high-quality, and high-purity small molecule modulators and inhibitors for studying the function of DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). We have a growing number of high-purity and specific inhibitors against these important enzymes. These small-molecule compounds are available in a variety of specifications and can be freely selected according to your experimental requirements.

Methyltransferases include a group of significant regulatory enzymes that catalyze the transfer of methyl groups to substrates like DNA and histones. Moreover, the methylation has vital physiological significance in eukaryotes. DNMTs and HMTs are two key enzymes in epigenetic mechanisms, whose dysfunction can lead to a range of diseases such as cancer, making them attractive targets for drug development. Modulators and inhibitors of DNA / histone methylation enable researchers to study diseases associated with methylation, especially cancer.

In addition to key inhibitors targeting DNMTs and HMTs, we also provide a large number of modulators and inhibitors against proteins / enzymes involved in demethylation. These small-molecule compounds can be used for enzyme activity studies and epigenetic drug discovery. If you do not find the ideal product in our catalog, please feel free to contact us and scientists from Creative BioMart will offer solutions according to your specific requirements.