| Cat.No.: | PE-1853 |
| Product Name: | BRDT bromodomains 1 and 2 (human recombinant) |
| Description: | The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. Bromodomain testis-specific (BRDT) shares homology with the RING3 protein. The two bromodomains of BRDT recognize acetylated histone H4. Loss of BRDT leads to defects in spermatogenesis. In addition to testis specific expression, BRDT was found in approximately 20% of non-small cell lung cancers. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 68.7 kDa |
| Purity: | ≥95% |
| Species: | human |
| Formulation: | 10 mM HEPES, pH 7.5, containing 500 mM sodium chloride and 5% glycerol |
| Alternative Names: | BRD6;Bromodomain testis-specific protein;Cancer/testis antigen 9;CT9;RING3-like protein |
| Tag: | GST |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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