| Cat.No.: | PE-3027 |
| Product Name: | G9a/GLP Complex Methyltransferase |
| Description: | In vivo, a heterodimeric complex of the related SET-domain histone methyltransferases (HMTs) G9a and GLP is the major source of mono- and dimethylated histone H3K9 in euchromatin, marks associated with recruitment of HP1, DNA methylation and gene silencing. Per mole of G9, GLP or (G9a + GLP), this equimolar mixture displays activity well in excess of G9a alone, similar to the more active GLP, suggesting a significant degree of heterodimer formation. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 80.0/80.00 kDa |
| Formulation: | Solution of purified recombinant proteins in 25.4 mM Na2HPO4/NaH2PO4, pH 7.4, 137 mM NaCl, 2.7 mM KCl, 3 mM DTT, 30% (w/v) glycerol. |
| Accession#: | NM_006709, NM_024757 |
| Tag: | GST |
| Protein Length: | G9a 786-1210 (C-term.), GLP 894-1298 (C-term.) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0025 | BIX01294 (hydrochloride hydrate) | Inquiry |
| BSM-0026 | UNC0224 | Inquiry |
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Cell Lines | ||
| CL-0059 | Human EHMT1 Knockout Cell Line 7bp deletion | Inquiry |
| CL-0060 | Human EHMT2 Knockout Cell Line 34bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EHD2 | EHMT1 | EHMT2 | |
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