| Cat.No.: | PE-3109 |
| Product Name: | BRD1 (His) |
| Description: | Human recombinant BRD1 bromodomain. Native BRD1 (BRPF-2) contains, in addition to its acetyllysine-binding bromodomain, two other histone binding domains—a PWWP domain (histone H3 K79me2/3 & K36me3 binding) and a PHD zinc-finger (PHD1, N-terminal tail, unmodified histone H3 binding)—as well as a DNA binding domain (PHD2). Although assumed, like fellow family members BRPF-1 and BRPF-3 to perform a scaffolding function as part of MOZ/MORF histone acetyltransferase (HAT) complexes, BRD1 has been shown to form a complex with another MYST-family HAT, HBO1, plus ING4, and to be required for H3K14 acetylation and erythropoiesis. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 18.2 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM Tris-HCl pH 7.5, pH 7.0, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v) |
| Accession#: | NM_014577 |
| Tag: | His |
| Protein Length: | 556-688 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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