| Cat.No.: | PE-3159 |
| Product Name: | CECR2 (His) |
| Description: | Human recombinant CECR2 bromodomain. CECR2, along with SMARCA1 (SNF2L) forms the ATP-dependent chromatin remodeling complex CERF and plays an essential role in neural tube formation. The CECR2 bromodomain displays binding affinity for mutiple histone H2A and H3 Lys(Ac) residues in singly acetylated histone peptide microarrays (H2A: K15Ac, K36Ac, K75Ac; H3: K9Ac, K14Ac, K18Ac & others), with the H3K9Ac and H3K14Ac interactions confirmed by isothermal titration calorimetry (ITC). A crystal structure for the CECR2 binding domain has been determined. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 16.4 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1.0 mM TCEP, 10% glycerol (v/v) |
| Accession#: | NM_031413 |
| Tag: | His |
| Protein Length: | 425-538 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0054 | Human CECR2 Knockout Cell Line 13bp deletion | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0191 | Human CENPA peptide | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0219 | Recombinant Human CENPA 293 Cell Lysate | Inquiry |
| EL-0220 | Recombinant Human CENPA 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0340 | NVS-CECR2-1 | Inquiry |
| Related Gene / Proteins | |||
| CEACAM1 | CECR1 | CECR2 | CELF-5 |
| CELF-6 | CENH3 | CENPA | CENPB |
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