| Cat.No.: | PE-3184 |
| Product Name: | ATAD2B (GST) |
| Description: | Human recombinant ATAD2B bromodomain. In addition to a bromodomain, native ATAD2B contains an AAA ATPase domain. Expressed and located to the nucleus during neuronal development (chick embryos), ATAD2B is expressed at elevated levels in some human tumors (glioblastoma, oligodendroglioma, breast cancer), but is present in the cytoplasm or membrane-bound fractions. The ATAD2B bromodomain binds various Lys(Ac) residues in singly acetylated histone peptide microarrays (histones H1.4, H2A, H2B, H3, H4) with binding to histone H4 K5(Ac) confirmed in solution by isothermal titration calorimetry (ITC). |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 42.6 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM HEPES/NaOH, pH 7.0, 500 mM NaCl, 1 mM TCEP, 10 % glycerol |
| Accession#: | NM_017552 |
| Tag: | GST |
| Protein Length: | 952-1086 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0020 | Human ATAD2 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0021 | Human ATAD2B Knockout Cell Line 130bp insertion | Inquiry |
| CL-0022 | Human ATAD2B Knockout Cell Line 130bp insertion | Inquiry |
| ◆ Research Kits | ||
| EKIT-0021 | ATF2 (pT69/pT71) Transcription Factor Assay Kit | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0031 | Recombinant Human ATAD2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ATAD2 | ATAT1 | ATF-6 | ATF1 |
| ATF2 | ATF4 | ATM | ATR |
| ATRX | ATXN3 | ATXN3L | ATXN7 |
| ATXN7L3 | |||
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