| Cat.No.: | PE-3187 |
| Product Name: | ASH1L- [BRD] (His) |
| Description: | Human recombinant ASH1L bromodomain. ASH1L is a large (333 kDa), multi-domain protein associated with actively transcribed regions of chromatin. Its bromodomain lies C-terminal to its SET domain, which confers histone H3K36 methyltransferase activity. ASH1L is the human homolog of Drosophila Ash1, a Trithorax group protein. Like its counterpart in Drosophila, ASH1L has been found to play a role in the regulation of Hox gene expression. The ASH1L bromodomain displays strong binding to various Lys(Ac) residues in singly acetylated histone peptide microarrays (histones H1.4K74Ac, H2AK36Ac, H2BK85Ac, H3K56Ac, H4K59Ac/K79Ac). |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 17.7 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM Tris HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v) |
| Accession#: | NM_018489 |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | 2428-2559 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0018 | Human ASH1L Knockout Cell Line 53bp deletion | Inquiry |
| CL-0019 | Human ASXL2 Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0162 | Recombinant Human ASH2L 293 Cell Lysate | Inquiry |
| EL-0173 | Recombinant Human ASF1A 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0168 | ASH2 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| ASB10 | ASB11 | ASB13 | ASB6 |
| ASB7 | ASB8 | ASB9 | ASF1 |
| ASH1L | ASH2 | ASXL2 | |
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