| Cat.No.: | PE-3296 |
| Product Name: | Histone H2AX, Recombinant Human |
| Description: | Recombinant human histone H2AX (H2AFX, accession P16104) expressed in E. coli and purified by FPLC. Histone H2AX is a histone variant that is incorporated into a subset of nucleosomes in place of canonical histone H2A. H2AX is phosphorylated on serine 139 by the ATM and ATR kinases in response to DNA double strand breakage. Phosphorylated H2AX serves as a platform to recruit a number of DNA damage repair proteins, including BRCA1, NBS1 and MDC1. |
| Applications: | Histone H2AX, Recombinant Human Recombinant histone H2AX is suitable for enzyme assays and nucleosome reconstitution. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 15 kDa |
| Species: | Human |
| Formulation: | lyophilized powder |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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