Recombinant THRβ protein


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Cat.No.:  PE-3390
Product Name:  Recombinant THRβ protein
Product Overview:  Recombinant human THRβ protein was expressed in a baculovirus expression system as the full length protein (accession number NP_000452.2) with an N-terminal FLAG tag. The molecular weight of the protein is 54.1 kDa.
Background:  THRβ (Thyroid Hormone Receptor Beta, also known as ERBA2) is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. THRβ is a high affinity receptor for thyroid hormones,including triiodothyronine and thyroxine. It can act as a repressor or activator of transcription.
Applications:  Suitable for use in the study of binding assay, inhibitor screening, and selectivity profiling
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Formulation:  25 mM HEPES-NaOH pH 7.5, 500 mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5 mM TCEP.
Tag:  FLAG
Expression System:  Baculovirus
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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