| Cat.No.: | PE-3732 |
| Product Name: | DNMT1 recombinant protein |
| Description: | Full length recombinant human N-terminal His tagged and C-terminal FLAG tagged DNMT1 (DNA (cytosine-5)-methyltransferase 1) protein, produced in Sf9 insect cells. |
| Background: | DNMT1 (UniProt/Swiss-Prot entry P26358) preferentially methylates CpG residues in hemimethylated DNA and is responsiblefor maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones.Inactivation of DNMT1 causes global demethylation and embryonic lethality. Transcriptional repression by DNMT1 is mediatedby direct interaction with HDAC2. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Purity: | Purified using FPLC, >98% purity as determined by SDS-PAGE |
| Species: | Human |
| Formulation: | 20 mM Tris-Cl pH 7.6, 100 mM EDTA, 0.15 MNaCl, 0.1% NP40 and 10% glycerol. |
| Alternative Names: | DNMT, MCMT, CXXC9, AIM |
| Tag: | His & FLAG |
| Expression System: | Sf9 Insect Cells |
| Concentrations: | 0.5 µg/µl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
