| Cat.No.: | PE-3736 |
| Product Name: | HP1α recombinant protein |
| Description: | Full length recombinant human N-terminal His tagged HP1α (Heterochromatin Protein 1 Homolog Alpha) protein,produced in E. coli. |
| Background: | HP1 alpha (UniProt/Swiss-Prot entry P45973) is a component of heterochromatin. It recognizes and binds to histone H3 tailsmethylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR),thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involvedin the formation of a functional kinetochore through interaction with MIS12 complex proteins. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Purity: | Purified using FPLC, >98% purity as determined by SDS-PAGE. |
| Species: | Human |
| Formulation: | 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 MNaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT. |
| Tag: | His |
| Expression System: | E. coli |
| Concentrations: | 0.5 µg/µl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0051 | Human CBX1 Knockout Cell Line 32bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0082 | HP1α, β and γ Polyclonal Antibody | Inquiry |
| EAb-0083 | HP1α Polyclonal Antibody | Inquiry |
| EAb-0149 | CBX1 Polyclonal Antibody | Inquiry |
| EAb-0677 | CBX1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| HP1 | HP1BP3 | ||
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