Bromodomain Testis-specific Protein (BrdT), human recombinant


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Cat.No.:  PE-3782
Product Name:  Bromodomain Testis-specific Protein (BrdT), human recombinant
Description:  The recombinant protein includes Bromo 1 domain (22-138 aa) with N-terminal His-tag.
Background:  BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  13.9 kDa (117aa, 22-138 +NT-His Tag)
Purity:  Purity by SDS-PAGE ≥98%
Formulation:  50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Accession#:  Q58F21
Alternative Names:  BrdT, Cancer/testis antigen 9, CT9, RING3-like protein
Tag:  His
Expression System:  E. coli
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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