Histone H3 (tri-methyl K4) Quantification Kit (Colorimetric)


  • Specification
  • Related Products
Cat.No.:  EKIT-0291
Product Name:  Histone H3 (tri-methyl K4) Quantification Kit (Colorimetric)
Assay Type:  Quantitative
Description:  Histone H3 (tri-methyl K4) Quantification Kit (Colorimetric) allows the user to specifically measure global tri-methylation of histone H3-K4 colorimetrically using a variety of mammalian cells (human, mouse, etc.) including fresh and frozen tissues, cultured adherent and suspension cells.Methylation of histone H3 at lysine 4 by Methyl transferases such as SET1, SET7/9, MLL and Trx among others occurs in mammals in several distinct genomic distributions. Enrichment of H3 (tri-methyl K4) is found at transcription start sites of active genes where they contribute to transcriptional initiation.
Background:  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Detection Method:  Colorimetric
Target Species:  Mouse, Human; Mammals
Warning:  For research use only, not for diagnostic use.

Online Inquiry

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

USA

Enter your email here to subscribe.

Follow us on

Easy access to products and services you need from our library via powerful searching tools

Copyright © Creative BioMart. All Rights Reserved.