Histone H3 (methyl K9) Assay Kit (In Situ)


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Cat.No.:  EKIT-0310
Product Name:  Histone H3 (methyl K9) Assay Kit (In Situ)
Assay Type:  Cell-based (quantitative)
Description:  Methylation of histone H3 at lysine 9 (K9) mediates heterochromatin formation by forming a binding site for HP1 and also participates in silencing expression at euchromatic sites. Moreover, presence of H3 (methyl K9) positively correlates with DNA methylation.Histone H3 (methyl K9) Assay Kit (In Situ) allows the user to specifically measure histone H3K9me in situ using cultured adherent cells in a quick and efficient procedure.
Background:  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Target Species:  Mouse; Mammals
Warning:  For research use only, not for diagnostic use.

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