Histone H3 (acetyl K9) Assay Kit (In Situ)


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Cat.No.:  EKIT-0331
Product Name:  Histone H3 (acetyl K9) Assay Kit (In Situ)
Assay Type:  Cell-based (quantitative)
Description:  Acetylation of histone H3 at lysine 9 (K9) is a mark of active chromatin and appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Increased H3 (acetyl K9) may also reflect a decrease in H3 (methyl K9) associated with gene repression.Histone H3 (acetyl K9) Assay Kit (In Situ) allows the user to measure in situ acetylation of histone H3K9 at tremendously fast speeds and consistency, superior and safer than all other current methods. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment. The kit is suitable for specifically measuring in situ histone H3K9 acetylation using cultured adherent cells.
Background:  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Target Species:  Mouse, Human; Mammals
Warning:  For research use only, not for diagnostic use.

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