Histone H3 (methyl K9) Assay Kit


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Cat.No.:  EKIT-0356
Product Name:  Histone H3 (methyl K9) Assay Kit
Assay Type:  Quantitative
Description:  Histone H3 (methyl K9) Assay Kit allows the user to specifically measure global histone H3K9 methylation using a variety of mammalian cells including fresh and frozen tissues, cultured adherent and suspension cells.Methylation of histone H3 at lysine 9 (K9) mediates heterochromatin formation by forming a binding site for HP1 and also participates in silencing expression at euchromatic sites. Moreover, presence of H3 (methyl K9) positively correlates with DNA methylation.
Background:  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Target Species:  Mouse, Human; Mammals
Warning:  For research use only, not for diagnostic use.

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