PRMT8 Homogeneous Assay Kit


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Cat.No.:  EKIT-0480
Product Name:  PRMT8 Homogeneous Assay Kit
Size:  384 reactions
Description:  The PRMT8 Homogeneous Assay Kit is designed to measure the activity of PRMT8 for screening and profiling applications, using AlphaLISA technology. The key to the PRMT8 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing PRMT8 enzyme is incubated with the biotinylated substrate for one hour. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.
Background:  PRMT8 is a histone methyltransferase that exhibits methylation activity toward histones H2A and H4.
Applications:  For studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Kit Components:  The PRMT8 Homogeneous Assay Kit comes in a convenient AlphaLISA format, with a 384-well plate, biotinylated histone H4 peptide substrate, primary antibody, methylation assay buffer, and purified PRMT8 for 384 enzyme reactions.
Warning:  For research use only, not for diagnostic use.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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