| Cat.No.: | BSM-0054 |
| Product Name: | (-)-Epigallocatechin gallate |
| CAS No.: | 989-51-5 |
| Figure: |
-Epigallocatechin gallate-1.jpg)
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| Synonyms: | EGCG; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate) |
| Description: | A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC₅₀= 86-194 nM) and in vivo (IC₅₀ =1 -10 µM). |
| Appearance: | Off-white to yellow solid |
| Molecular Weight: | 458.37 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | DNA methyltransferase (DNMT) |
| Molecular Formula: | C₂₂H₁₈O₁₁ |
| MDL Number: | MFCD00075940 |
| Solubility: | DMSO or EtOH |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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