| Cat.No.: | BSM-0149 |
| Product Name: | I-BET762 |
| CAS No.: | 1260907-17-2 |
| Figure: |
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| Synonyms: | (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide; GSK525762 |
| Description: | I-BET762 (GSK525762) is a highly potent, selective and cell-permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 (IC50 of ~35 nM).It has been shown to bind to the acetylated lysine recognition motifs on thebromodomain of BET proteins. This binding prevents the interaction of between BET proteinsand acetylated histone peptides. |
| Appearance: | Off-white solid |
| Molecular Weight: | 423.9 |
| Purity: | >98% by HPLC |
| Storage: | -20 ̊C |
| Targets: | Bromodomain |
| Molecular Formula: | C22H22ClN5O2 |
| MDL Number: | MFCD04000098 |
| Solubility: | DMSO or EtOH |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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