N-Oxalylglycine


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Cat.No.:  BSM-0177
Product Name:  N-Oxalylglycine
CAS No.:  5262-39-5
Figure: 
Synonyms:  2-(Carboxymethylamino)-2-oxoacetic acid
Description:  N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell-permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC₅₀s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC₅₀ values of 2.1 and 5.6 μM, respectively.
Appearance:  White Solid
Molecular Weight:  147.1
Purity:  ≥95% by HPLC
Storage:  -20°C
Targets:  α-ketoglutarate-dependent enzymes
Molecular Formula:  C₄H₅NO₅
MDL Number:  MFCD00913253
Solubility:  DMSO (~10 mg/ml)
Shipping Conditions:  Gel Pack
Warning:  For Research Use Only! Not For Use in Humans.

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