| Cat.No.: | EL-0200 |
| Product Name: | Recombinant Human TAF6L Cell Lysate |
| Description: | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. |
| Species: | Human |
| Warning: | For research use only, not for diagnostic or therapeutic use. |
| Gene ID NCBI: | 10629 |
| Official Symbol: | TAF6L |
| Official Full Name: | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor |
| Synonyms: | TAF6L; TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF6 like RNA polymerase II, p300/CBP associated factor (PCAF) associated factor, 65 kD; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; PAF65A; PAF65-alpha; PCAF-associated factor 65 alpha; PCAF-associated factor 65-alpha; p300/CBP-associated factor (PCAF)-associated factor 65; MGC4288; FLJ11136; |
| mRNA Refseq: | NM_006473 |
| Protein Refseq: | NP_006464 |
| MIM: | 602946 |
| UniProt ID: | Q9Y6J9 |
| Chromosome Location: | 11q12.3 |
| Function: | DNA binding; contributes_to histone acetyltransferase activity; protein binding; transcription coactivator activity; |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0017 | TAF1 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0056 | Recombinant Human TAL1 293 Cell Lysate | Inquiry |
| EL-0108 | Recombinant Human TAF7 293 Cell Lysate | Inquiry |
| EL-0178 | Recombinant Human TADA1 Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0121 | Human TAP2 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| TADA1 | TADA1L | TADA2A | TADA2B |
| TADA3 | TAE1 | TAF-I | taf1 |
| TAF1L | TAF6L | TAF7 | TAF7L |
| TAL1 | TAP2 | TAZ | |
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