Cat.No.: | EAb-0132 |
Product Name: | H3K18ac Polyclonal Antibody |
Product Overview: | Polyclonal Antibody to detect H3K18ac in human samples. |
Antibody Type: | Polyclonal |
Immunogen: | Synthetic peptide corresponding to Human Histone H3 (acetyl K18) conjugated to keyhole limpet haemocyanin. |
Host: | Rabbit |
Isotype: | IgG |
Antibody Target: | H3K18ac |
Purification: | Affinity purified |
Appearance: | Colorless liquid |
Formulation: | In PBS with 0.05% (W/V) sodium azide. |
Applications: | Western blot, ELISA, Dot Blot. |
Recommended Dilutions/Conditions: |
WB: 1:250, ELISA: 1:100, Dot Blot: 1:1,000. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Positive Control: | Western blot: HeLa cells, ELISA: Antigen, Dot blot: Histone Peptides. |
Species Reactivity: | Human |
Shipping: | Gel Pack |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | P68431 |
Alternative Name: | Histone 3 |
Scientific Background: | Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of histone H3 is associated with active gene transcription. |
Product Types | ||
◆ Research Kits | ||
EKIT-0001 | Acetyl Histone H3-K14 Quantification Kit (Colorimetric) | Inquiry |
EKIT-0002 | Acetyl Histone H3-K14 Quantification Kit (Fluorometric) | Inquiry |
EKIT-0003 | Acetyl Histone H3-K18 Quantification Kit (Colorimetric) | Inquiry |
EKIT-0004 | Acetyl Histone H3-K18 Quantification Kit (Fluorometric) | Inquiry |
EKIT-0005 | Acetyl Histone H3-K23 Quantification Kit (Colorimetric) | Inquiry |
Related Gene / Proteins | |||
H3K10 | H3K115 | H3K122 | H3K123 |
H3K14 | H3K18 | H3K23 | H3K27 |
H3K36 | H3K37 | H3K4 | H3K5 |
H3K56 | H3K64 | H3K79 | H3K80 |
H3K9 | H3R128 | H3R17 | H3R2 More > |
H3R26 | H3R8 | H3R9 | H3S10 |
H3S28 | H3S31 | H3S32 | H3T11 |
H3T118 | H3T3 | H3T32 | H3T41 |
H3T45 | H3T6 | H3T80 | H3Y41 |
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