| Cat.No.: | EAb-0138 |
| Product Name: | EZH2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide mapping to the N-terminus of rat Ezh2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | EZH2 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | 100 µg (0.5 mg/ml) affinity purified rabbit anti- EZH2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal. |
| Applications: | Western blot |
| Recommended Dilutions/Conditions: |
Western Blot analysis (0.5-4 µg/ml). Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Rat kidney tissue lysate |
| Species Reactivity: | Human, mouse, rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q15910 |
| Alternative Name: | EZH2; ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2; histone-lysine N-methyltransferase EZH2 |
| Scientific Background: | Enhancer of zeste homolog 2 (Ezh2) is a member of the Polycomb group (PcG). The PcG proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. Enhancer of zeste homolog 2 (Ezh2) contains four conserved regions including domain I, domain II, and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. Ezh2 also plays a role as primary effector and as a mediator of tumorigenesis. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| BSM-0059 | 3-Deazaneplanocin A | Inquiry |
| BSM-0060 | 3-Deazaneplanocin A hydrochloride | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ezh1 | EZH2 | ||
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