BRDT Polyclonal Antibody


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Cat.No.:  EAb-0155
Product Name:  BRDT Polyclonal Antibody
Product Overview:  Polyclonal Antibody to detect BRDT in human samples
Antibody Type:  Polyclonal
Immunogen:  Recombinant protein BRDT (22-138 aa) (BV-M60)
Host:  Rabbit
Isotype:  IgG
Antibody Target:  BRDT
Purification:  Affinity Purified Antibody
Appearance:  Colorless liquid
Formulation:  100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Applications:  Western blot
Recommended Dilutions/Conditions:  Western blot: ~1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  Western blot: Recombinant protein
Species Reactivity:  Human
Shipping:  Gel Pack
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q58F21
Alternative Name:  BrdT, Cancer/testis antigen 9, CT9, RING3-like protein
Scientific Background:  BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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