PRMT1 Polyclonal Antibody


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Cat.No.:  EAb-0233
Product Name:  PRMT1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to a portion of human PRMT1.
Host:  Rabbit
Purification:  Protein G affinity purified.
Appearance:  Liquid
Formulation:  In PBS containing 0.09% sodium azide.
Applications:  ELISA, IHC, WB
Recommended Dilutions/Conditions:  ELISA (1:1,000)Immunohistochemistry (1:50-1:100)Western Blot (1:100-1:500).
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Shipping:  Blue Ice
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q99873
Alternative Name:  SKB, PRDM1
Scientific Background:  Protein arginine N-methyltransferases (PRMTs) catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a guanidine nitrogen of arginine. PRMT1 methylates arginine residues in glycine-rich areas of histone H4 as well as many non-histone substrates that regulate transcriptional activation, mRNA processing, and signal transduction. In contrast, PRMT5 methylates arginines in proline-, glycine-, methionine-rich motifs and is known to interact with Jak kinases. PRMT2 inhibits NF-κB-dependent transcription and promotes apoptosis.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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