| Cat.No.: | EAb-0234 |
| Product Name: | RbAp46 Polyclonal Antibody (biotin conjugate) |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to aa 1-13 (MASKEMFEDTVEEC) of human RbAp46. |
| Host: | Rabbit |
| Isotype: | IgG |
| Specificity: | Recognizes human RbAp46. |
| Purification: | Antigen affinity chromatography |
| Appearance: | Liquid |
| Formulation: | In PBS containing 1mg/ml BSA and 0.05% sodium azide. |
| Applications: | ICC, IF, IHC, WB |
| Species Reactivity: | Human |
| Shipping: | Blue Ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q16576 |
| Alternative Name: | Histone-binding protein RBBP7, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, Histone acetyltransferase type B subunit |
| Scientific Background: | RbAp46 is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex as are the histone deacetylase proteins (HDACs). RbAp46 shares about 75% sequence identity with the closely related RbAp48, and appears to be functionally related to the yeast MSI1 protein in that overexpression of RbAp46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RbAp46 has also been demonstrated to be up-regulated by the Wilms’ tumor suppressor gene product, WT1. Additionally, cells transfected with RbAp46 have shown strong inhibition of growth. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0043 | RBBP4 Polyclonal Antibody | Inquiry |
| EAb-0181 | RBM26 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0047 | Recombinant Human RBBP4 Cell Lysate | Inquiry |
| EL-0216 | Recombinant Human RBBP5 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0118 | Human RBBP7 Knockout Cell Line 5bp deletion | Inquiry |
| Related Gene / Proteins | |||
| RB1 | RbAp46 | RbAp48 | RBB4L |
| RBBP2 | RBBP4 | RBBP5 | RBBP7 |
| RBBP9 | RBM11 | RBM18 | RBM26 |
| RBM3 | RBM34 | RBM38 | RBM39 |
| RBM41 | RBM42 | RBM46 | RBM5 More > |
| RBM7 | RBMS1 | RBMS2 | RBMS3 |
| RBMY1A1 | RBMY1F | RBPJ | RBPMS |
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