SET07 Monoclonal Antibody (43AT551.86.76)


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Cat.No.:  EAb-0240
Product Name:  SET07 Monoclonal Antibody (43AT551.86.76)
Antibody Type:  Monoclonal
Immunogen:  Recombinant human SET07 (N-terminal fragment).
Host:  Mouse
Isotype:  IgG1
Purification:  Peptide affinity purified.
Appearance:  Liquid
Formulation:  In PBS containing 0.09% sodium azide.
Applications:  ELISA, WB
Recommended Dilutions/Conditions:  ELISA (1:1,000)Western Blot (1:100-1:500).
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Shipping:  Blue Ice
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q8WTS6
Scientific Background:  SET07 is a histone methyltransferase that methylates Lys20 of histone H4, a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of the H4 tail.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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