| Cat.No.: | EAb-0243 |
| Product Name: | [pSer139]Histone H2AX Monoclonal Antibody (9F3) |
| Antibody Type: | Monoclonal |
| Immunogen: | Synthetic peptide corresponding to a portion of human Histone H2AX phosphorylated at Ser139. |
| Host: | Mouse |
| Isotype: | IgG1κ |
| Purification: | Purified from hybridoma tissue culture supernatant. Protein G affinity purified. |
| Appearance: | Liquid |
| Formulation: | In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| Applications: | WB |
| Recommended Dilutions/Conditions: |
Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, RatBovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit |
| Shipping: | Blue Ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P16104 |
| Scientific Background: | The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The core histones form an octamer, which is made up of one H3-H4 tetramer and two H2A-H2B dimers. The N-terminal tail of core histones undergoes different post-transcriptional modifications including acetylation, phosphorylation, methylation and ubiquitination. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0020 | Recombinant Nucleosome, H2AR3me1 dNuc | Inquiry |
| NUC-0021 | Recombinant Nucleosome, H2AR3me2a dNuc | Inquiry |
| NUC-0075 | Recombinant Nucleosome, H2AK119ub dNuc | Inquiry |
| NUC-0076 | Recombinant Nucleosome, H2BK120ub dNuc | Inquiry |
| NUC-0082 | Recombinant Nucleosome, H2AXS139phos dNuc | Inquiry |
| Related Gene / Proteins | |||
| H2AK11 | H2AK119 | H2AK12 | H2AK13 |
| H2AK15 | H2AK16 | H2AK4 | H2AK5 |
| H2AK7 | H2AK8 | H2AK9 | H2AP26 |
| H2AQ104 | H2AR29 | H2AR3 | H2AS1 |
| H2AS129 | H2AS139 | H2AS2 | H2AT120 More > |
| H2AT121 | H2AT142 | H2AY142 | H2BK108 |
| H2BK11 | H2BK116 | H2BK12 | H2BK120 |
| H2BK126 | H2BK15 | H2BK16 | H2BK20 |
| H2BK23 | H2BK43 | H2BK46 | H2BK5 |
| H2BR79 | H2BS112 | H2BS14 | H2BS32 |
| H2BT129 | |||
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