| Cat.No.: | EAb-0257 |
| Product Name: | Histone H3 Monoclonal Antibody (Clone 2B8) |
| Description: | Histone H3 monoclonal antibody (clone 2B8) can be used for ELISA and western blot applications. The antibody recognizes histone H3 at 17 kDa from human samples. |
| Antibody Type: | Monoclonal |
| Clone Designation: | 2B8 |
| Immunogen: | Recombinant Histone H3 protein |
| Host: | Mouse |
| Isotype: | IgG2a |
| Appearance: | Liquid |
| Formulation: | 100 µg of protein G-purified IgG |
| Applications: | ELISA, WB |
| Species Reactivity: | Human H3 |
| Shipping: | Wet ice |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, with 50% glycerol with 0.1% BSA and 0.02% sodium azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P68431 |
| Scientific Background: | A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H3 undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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