I2PP2A/SET Polyclonal Antibody


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Cat.No.:  EAb-0269
Product Name:  I2PP2A/SET Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  synthetic peptides from human I2PP2A/SET amino acids 79-94 and 148-164
Host:  Rabbit
Appearance:  Liquid
Formulation:  100 µl of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide and 0.1 mg/ml BSA
Applications:  WB
Species Reactivity:  Human I2PP2A/SET
Shipping:  Wet ice
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Inhibitor of granzyme A-activated DNase;Phosphatase 2A Inhibitor;Template-Activating Factor I;PHAPII
Scientific Background:  I2PP2A/SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly, and histone binding. The SET gene produces two isoforms from transcript variants. Isoform 1 and 2 interact directly with each other and with ANP32A within the tripartite inhibitor of acetyltransferases (INHAT) complex, inhibiting EP300/CREBBP and PCAF-mediated acetylation of histones.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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