SET7/9 (FL) Polyclonal Antibody


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Cat.No.:  EAb-0271
Product Name:  SET7/9 (FL) Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Human recombinant SET7/9 amino acids 1-366
Host:  rabbit
Appearance:  Liquid
Formulation:  400 µg of protein A-purified antibody
Applications:  WB
Species Reactivity:  Human, Mouse
Shipping:  Wet ice
Storage:  -20°C
Storage Buffer:  PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q8WTS6
Alternative Name:  KMT7;SETD7/9;SET Domain-Containing Protein 7/9
Scientific Background:  Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly (ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. SET7/9 utilizes S-adenosylmethionine to methylate histone H3 at lysine 4. Human SET7/9 is a 366 amino acid protein with observed migration on SDS-PAGE at 49 kDa.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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