SET7/9 Polyclonal Antibody


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Cat.No.:  EAb-0272
Product Name:  SET7/9 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  human SET7/9 amino acids 131-145 and 336-352
Host:  rabbit
Appearance:  Liquid
Formulation:  200 µl of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Applications:  WB
Species Reactivity:  Human SET7/9, Mouse SET7/9
Shipping:  Wet ice
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. SET7/9 is a histone specific HMTase that methylates histone H3 lysine 4. SET7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human SET7/9 is a 366 amino acid protein.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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