| Cat.No.: | EAb-0289 |
| Product Name: | Acetyl-Histone Monoclonal Antibody (7F8) |
| Description: | This antibody is useful for monitoring levels of acetylation (i.e., histones and p53). This monoclonal antibody was generated using acetylated KLH as an immunogen. |
| Antibody Type: | Monoclonal |
| Clone Designation: | 7F8 |
| Immunogen: | Peptide from acetylated KLH |
| Host: | mouse |
| Isotype: | IgG1 |
| Appearance: | Liquid |
| Formulation: | 100 µg of ammonium sulfate precipitated antibody |
| Applications: | ELISA, ICC, and WB |
| Shipping: | Room temperature |
| Storage: | -20°C |
| Storage Buffer: | TBS, pH 7.4, with 50% glycerol, 0.1% BSA, and 0.02% sodium azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | ACE |
| Scientific Background: | Histone subunit modifications such as lysine acetylation are regulated by the activity of histone acetyltransferases (HATs) and histone deacetylases (HDACs). Epigenetic modifications directly influence cellular genetic programs including those contributing to cancer cell viability. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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