| Cat.No.: | EAb-0348 |
| Product Name: | Histone H3 Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | Recombinant Protein |
| Host: | Mouse |
| Isotype: | IgG |
| Purification: | Protein A purification |
| Appearance: | Liquid |
| Applications: | WB, IHC-p, IF, IP |
| Recommended Dilutions/Conditions: |
WB: 1:500-1:2000; IHC: 1:50-300; IF: 1:100-500, IP 1:100-1:300 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat, Yeast |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P68431, Q71DI3, P84243 |
| Alternative Name: | HIST1H3A,H3FA,HIST1H3B,H3FL,HIST1H3C,H3FC,HIST1H3D,H3FB,HIST1H3E,H3FD,HIST1H3F,H3FI,HIST1H3G,H3FH,HIST1H3H,H3FK,HIST1H3I,H3FF,HIST1H3J,H3FJ,Histone H3.1,Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/ |
| Scientific Background: | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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