SMARCE1 Polyclonal Antibody


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Cat.No.:  EAb-0358
Product Name:  SMARCE1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant protein of human SMARCE1
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB, IF, IP
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000; IF: 1:50 - 1:200; IP: 1:20 - 1:50
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Storage Buffer:  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q969G3
Alternative Name:  BAF57,BRG1 associated factor 57,BRG1-associated factor 57,Chromatin remodeling complex BRG1 associated factor 57,FLJ35648,SMARCE 1,SMARCE1,SMCE1,SWI/SNF related matrix associated actin dependent regulator of chromatin e1,SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Scientific Background:  The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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