Cat.No.: | EAb-0372 |
Product Name: | SIRT3 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | A synthetic peptide of human SIRT3 |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Affinity purification |
Appearance: | Liquid |
Applications: | WB, IHC, IF |
Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human, Mouse, Rat |
Storage: | -20°C |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Q9NTG7 |
Alternative Name: | hSIRT 3,hSIRT3,Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase,NAD dependent deacetylase sirtuin 3 mitochondrial,NAD-dependent protein deacetylase sirtuin-3,mitochondrial,Regulatory protein SIR2 homolog 3,Silent mating type information regulation 2 S.cerevisiae homolog 3,Sir 2 like 3,SIR 2 like protein 3,SIR 3,SIR2 L3,Sir2 like 3,SIR2 like protein 3,SIR2-like protein 3,SIR2L3,SIR3,SIRT 3,SIRT3,Sirtuin 3,Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae),Sirtuin type 3,Sirtuin3 |
Scientific Background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
◆ Synthetic Peptides | ||
SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
Related Gene / Proteins | |||
Siah2 | SIK1 | SIMC1 | SIN3A |
SIN3B | SIP1 | Sir2p | SIRT |
SIRT1 | SIRT2 | SIRT3 | SIRT4 |
SIRT5 | sirt6 | SIRT7 | SIX3 |
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