| Cat.No.: | EAb-0373 |
| Product Name: | ARIH2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide of human ARIH2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, ELISA |
| Recommended Dilutions/Conditions: |
WB: 1:500-1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | O95376 |
| Alternative Name: | HT005,all trans retinoic acid inducible RING finger,Ari 2,Ari-2,ARI2,ARI2,Ariadne 2,Ariadne 2 protein homolog,ariadne homolog 2 (Drosophila),ariadne homolog 2,Ariadne RBR E3 ubiquitin protein ligase 2,ARIH 2,Arih2,E3 ubiquitin protein ligase ARIH2,E3 ubiquitin-protein ligase ARIH2,protein ariadne 2 homolog,Protein ariadne-2 homolog,Triad 1,TRIAD1,Triad1 protein,UIP48 |
| Scientific Background: | TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0001 | Human ARHGEF1 Knockout Cell Line 8bp deletion | Inquiry |
| CL-0002 | Human ARHGEF15 Knockout Cell Line | Inquiry |
| CL-0003 | Human ARHGEF11 Knockout Cell Line | Inquiry |
| CL-0004 | Human ARHGEF10L Knockout Cell Line | Inquiry |
| CL-0005 | Human ARHGEF12 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| ARD1A | ARF1 | ARHGEF1 | ARHGEF10 |
| ARHGEF10L | ARHGEF11 | ARHGEF12 | ARHGEF15 |
| ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF19 |
| ARID1A | ARID1B | ARID2 | ARID3A |
| ARID4A | ARID5A | ARID5B | ARIH2 More > |
| AROS | ARTD10 | ||
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