| Cat.No.: | EAb-0515 |
| Product Name: | JMJD2B Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | The immunogen recognized by this antibody maps to a region between residue 625 and 675 of human jumonji domain containing 2B using the numbering given in entry NP_055830.1 (GeneID 23030). |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | KDM4B |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | Tris-Citrate/Phosphate (pH 7.0 - 8.0) |
| Applications: | WB, ChIP, IP |
| Recommended Dilutions/Conditions: |
Western Blot; Chromatin Immunoprecipitation 1:10-1:500; Immunoprecipitation 2-5 ug/mg lysate Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Chicken |
| Storage: | -20°C |
| Storage Buffer: | 0.09% Sodium Azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | EC 1.14.11; FLJ44906; JHDM3B; JmjC domain-containing histone demethylation protein 3B; JMJD2BEC 1.14.11.-; jumonji domain containing 2B; Jumonji domain-containing protein 2B; KIAA0876lysine-specific demethylase 4B; lysine (K)-specific demethylase 4B |
| Scientific Background: | JMJD2B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. JMJD2B has been shown to be capable of antagonizing H3K9 trimethylation. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
| EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
| EAb-0075 | JMJD2b Polyclonal Antibody | Inquiry |
| EAb-0076 | JMJD2A Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JMJD | JMJD1A | JMJD1B | JMJD1C |
| JMJD2 | JMJD2A | JMJD2B | JMJD2C |
| JMJD2D | JMJD2E | JMJD2F | JMJD3 |
| JMJD4 | JMJD5 | JMJD6 | |
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