Histone H3K37me1 Polyclonal Antibody


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Cat.No.:  EAb-0519
Product Name:  Histone H3K37me1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Synthetic methylated peptide surrounding Lysine 37 of human Histone H3 [Swiss Prot Q71DI3].
Host:  Rabbit
Isotype:  IgG
Antibody Target:  HIST2H3C, Monomethyl Lys37
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  PBS and 30% Glycerol
Applications:  WB, DB, ChIP (-), ICC/IF (-)
Recommended Dilutions/Conditions:  Western Blot 1ug/ml; Dot Blot 1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, C. Elegans, Rat, Chicken, Drosophilia, Plant, Xenopus
Storage:  -20°C
Storage Buffer:  0.05% Sodium Azide
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  H3 histone, family 3A; H3.3AH3F3H3F3B; H3.3B; H3F3A; Histone H3; histone H3.3; MGC87782; MGC87783
Scientific Background:  Chromatin is the arrangement of DNA and proteins in which chromosomes are formed. Correspondingly, chromatin is formed from nucleosomes, which are comprised of a set of four histone proteins (H2A, H2B, H3, H4) wrapped with DNA. Chromatin is a very dynamic structure in which numerous post-translational modifications work together to activate or repress the availability of DNA to be copied, transcribed, or repaired. These marks decide which DNA will be open and commonly active (euchromatin) or tightly wound to prevent access and activation (heterochromatin). Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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